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  • Title: Three-dimensional structure of S-adenosyl-L-homocysteine hydrolase from Plasmodium falciparum.
    Author: Tanaka N, Nakanishi M, Kusakabe Y, Shiraiwa K, Yabe S, Ito Y, Kitade Y, Nakamura KT.
    Journal: Nucleic Acids Symp Ser (Oxf); 2004; (48):281-2. PubMed ID: 17150588.
    Abstract:
    Structural information of Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase (PfSAHH) has been expected to provide new-type chemotherapeutic agents against malaria. Here we report the crystal structure of PfSAHH. The present structure should provide opportunities to design potent and selective PfSAHH inhibitors.
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