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  • Title: Electrochemical detection of DNA single base mismatch by the use of strand exchange reaction.
    Author: Kumamoto S, Maruyama A, Nakamura M, Yamana K.
    Journal: Nucleic Acids Symp Ser (Oxf); 2006; (50):93-4. PubMed ID: 17150833.
    Abstract:
    The electrochemical method based on the strand exchange reaction (SER) for the detection of DNA single-base mismatch has been developed. Different electrochemical responses due to the slower SER rates for mismatch containing DNA than fully matched DNA were observed by using the redox-modified partial duplex DNA immobilized on gold electrode as an analytical probe.
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