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  • Title: Synthesis and antiviral properties of aza-analogues of acyclovir.
    Author: Koszytkowska-Stawińska M, Kaleta K, Sas W, De Clercq E.
    Journal: Nucleosides Nucleotides Nucleic Acids; 2007; 26(1):51-64. PubMed ID: 17162587.
    Abstract:
    Aza-analogues of Acyclovir were obtained from N-(2-pivaloyloxyethyl)-N-(pivaloyloxymethyl)-p-toluenesulfonamide via a one-pot base silylation/nucleoside coupling procedure. The antiviral activities of all aza-nucleosides in vitro against a variety of viruses were evaluated. None of these compounds displayed any specific antiviral effects.
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