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  • Title: [Clinical and pathological study of tumor marker in benign prostatic hypertrophy and incidental prostatic cancer].
    Author: Sakai N, Ogawa T, Ishibashi Y, Fukuoka H, Sakanishi S.
    Journal: Hinyokika Kiyo; 1991 Jun; 37(6):589-94. PubMed ID: 1716409.
    Abstract:
    To determine the value of prostatic markers for prostate cancer, serum prostatic acid phosphatase (PAP), prostate specific antigen (PSA) and gamma-Seminoprotein (gamma-Sm) were measured in 81 patients with benign prostatic hypertrophy and in 12 patients with incidental prostatic cancer. gamma-Sm was the most sensitive but the least specific of the three markers. Large prostate glands, especially hyper-glandular type tended to be associated with high gamma-Sm levels in our study. Patients with acute urinary retention, acute prostatitis and necrosis also showed positive markers. Out of 12 patients with incidental cancer, 5 patients had more than 2 elevated markers. Four patients with poorly differentiated adenocarcinoma failed to show increased markers.
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