These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Prolonged course of familial hemophagocytic lymphohistiocytosis.
    Author: Steinberg O, Yacobovich J, Dgany O, Kodman Y, Livni G, Rachmel A, Stein J, Yaniv I, Tamary H.
    Journal: J Pediatr Hematol Oncol; 2006 Dec; 28(12):831-3. PubMed ID: 17164654.
    Abstract:
    Familial hemophagocytic lymphohistiocytosis is usually diagnosed in the first 2 years of life and, if untreated, is rapidly fatal. We describe a 10-year-old boy with a 9-year history of prolonged fever and progressive hepatosplenomegaly who was diagnosed as having hemophagocytic lymphohistiocytosis 2, being homozygote to a previously described mutation in the PRF1 gene, and cured by the HLH-2004 protocol and allogenic bone marrow transplantation. This unique case emphasizes the heterogeneity of this disease and the diversity of its clinical presentations.
    [Abstract] [Full Text] [Related] [New Search]