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  • Title: Postevacuation hCG levels and risk of gestational trophoblastic neoplasia among women with partial molar pregnancies.
    Author: Growdon WB, Wolfberg AJ, Feltmate CM, Goldstein DP, Genest DR, Chinchilla ME, Berkowitz RS, Lieberman ES.
    Journal: J Reprod Med; 2006 Nov; 51(11):871-4. PubMed ID: 17165432.
    Abstract:
    OBJECTIVE: To develop human chorionic gonadotropin (hCG) criteria that determine a patient's risk of developing persistent gestational trophoblastic neoplasia (GTN) or achieving remission after partial mole evacuation. STUDY DESIGN: We used a database from the New England Trophoblastic Disease Center to analyze hCG levels from 284 women with partial molar pregnancies diagnosed between 1973 and 2003. RESULTS: An hCG level >199 mIU/mL in the third through eighth week following molar evacuation was associated with at least a 35% risk of GTN. CONCLUSION: Women with partial mole who have elevated hCG levels within the first few weeks after molar evacuation are at increased risk for developing GTN.
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