These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Assembly of 3-acyloxindoles via cui/L-proline-catalyzed intramolecular arylation of beta-keto amides.
    Author: Lu B, Ma D.
    Journal: Org Lett; 2006 Dec 21; 8(26):6115-8. PubMed ID: 17165943.
    Abstract:
    [Structure: see text] Intramolecular coupling of beta-keto 2-iodoanilides catalyzed by CuI/L-proline in DMSO occurs at room temperature, affording substituted 3-acyloxindoles in good yield. Electronic effects on the aromatic ring have little influence on this reaction. Variations at the 1, 3, 4, 5, and 6 positions of the oxindoles were achieved by employing the corresponding amides.
    [Abstract] [Full Text] [Related] [New Search]