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  • Title: Identification of a Moraxella catarrhalis gene that confers adherence to various human epithelial cell lines in vitro.
    Author: Lipski SL, Holm MM, Lafontaine ER.
    Journal: FEMS Microbiol Lett; 2007 Feb; 267(2):207-13. PubMed ID: 17166229.
    Abstract:
    Moraxella catarrhalis is a pathogen of the human airways. We found that expression of the M. catarrhalis gene mcmA by Escherichia coli increases adherence to epithelial cells 100-fold. Furthermore, we discovered that disrupting mcmA decreases M. catarrhalis adherence to laryngeal and lung cells, which are relevant to pathogenesis by the bacterium.
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