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  • Title: Microvascular decompression vs. gamma knife radiosurgery for typical trigeminal neuralgia: preliminary findings.
    Author: Brisman R.
    Journal: Stereotact Funct Neurosurg; 2007; 85(2-3):94-8. PubMed ID: 17167238.
    Abstract:
    BACKGROUND: Patients with typical trigeminal neuralgia were treated by one neurosurgeon with either microvascular decompression (MVD) or Gamma Knife radiosurgery (GKRS) and were prospectively evaluated with a uniform protocol. METHOD: GKRS was done with 75 Gy maximum to the cisternal trigeminal nerve near the pons. MVD was done without cauterizing or cutting the trigeminal nerve. RESULTS: Twenty-four patients were treated with MVD and 61 with GKRS. Complete pain relief (no pain no medicines) occurred at 12 and 18 months in 68 and 68% of patients treated with MVD and 58 and 24% with GKRS (p = 0.089), and >or=90% pain relief (with or without medicine) at 12 and 18 months in 90 and 78% with MVD and 75 and 48% with GKRS (p = 0.171). There were no permanent complications. CONCLUSION: Although many trigeminal neuralgia patients treated with either MVD or GKRS have pain relief, MVD is more likely than GKRS to result in complete pain relief.
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