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  • Title: [Combined use of local and systemic radiomodifiers as a new modality of cervical carcinoma therapy].
    Author: Neklasova NIu, Zharinov GM, Vinokurov VL, Skrynditsa GM.
    Journal: Vopr Onkol; 2006; 52(5):560-4. PubMed ID: 17168367.
    Abstract:
    A cooperative study included 643 cervical carcinoma patients (stage II-III). Radiotherapy used such local and systemic radiomodifiers as DMSO-dissolved metronidazole, which inhibited allopurinol DNA reparations, and dipyridamol, an inductor of interferon synthesis. A 13-15% rise in survival matched the results of combined treatment for cervical carcinoma, yet the simplicity of operation, accessibility, high efficiency and stability of results of our modality made it quite competitive in therapy of the disease.
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