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  • Title: Deepening ribosomal insights.
    Author: Liljas A.
    Journal: ACS Chem Biol; 2006 Oct 24; 1(9):567-9. PubMed ID: 17168551.
    Abstract:
    The remarkable progress of cryo-electron microscopy and crystallography in elucidating ribosomal structure and function continues. Most recently, two papers about complete 70S ribosomes from Thermus thermophilus at 2.8- and 3.7-A resolution give us more details about the conformations of bound transfer RNA (tRNA) molecules; the bridges between subunits; the locations and roles of proteins, magnesium ions, and water molecules; and the dynamics of ribosomes. Very significant new insights have been gained, particularly for the tRNAs, which can only be studied in their entirety in full ribosomes.
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