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Title: Regulation and specificity of S-nitrosylation and denitrosylation. Author: Tannenbaum SR, White FM. Journal: ACS Chem Biol; 2006 Nov 21; 1(10):615-8. PubMed ID: 17168564. Abstract: Signal transduction from nitric oxide (NO) is important in physiological processes such as smooth muscle relaxation and neurotransmission. NO signaling occurs through a variety of mechanisms, including S-nitrosylation (SNO) of sulfhydryl groups in protein. A paper in this issue of the journal dissects the regulatory system involved in SNO of caspase-3 and highlights the need for more direct investigations of the complex biological regulation by NO signaling.[Abstract] [Full Text] [Related] [New Search]