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PUBMED FOR HANDHELDS

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  • Title: Validation study of fractional exhaled nitric oxide measurements using a handheld monitoring device.
    Author: Gill M, Graff GR, Adler AJ, Dweik RA.
    Journal: J Asthma; 2006 Dec; 43(10):731-4. PubMed ID: 17169823.
    Abstract:
    We tested reproducibility of exhaled nitric oxide (FE(NO)) and inter-operator handling when measured with a handheld device, NIOX MINO. We enrolled 20 volunteers using a priori goals of acceptable reproducibility to be mean within-subject standard deviation less than 3 parts per billion (ppb) for FE(NO) measurements less than 30 ppb, and mean coefficient of variation less than 10% for FE(NO) measurements more than 30 ppb. Seventeen subjects with measurements less than 30 ppb displayed a mean standard deviation of 1.15, and 3 subjects with FE(NO) more than 30 ppb had a mean coefficient of variation of 2.4%. We conclude that NIOX MINO demonstrates excellent reproducibility for all ranges of FE(NO).
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