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  • Title: Synthesis and activity of Combretastatin A-4 analogues: 1,2,3-thiadiazoles as potent antitumor agents.
    Author: Wu M, Sun Q, Yang C, Chen D, Ding J, Chen Y, Lin L, Xie Y.
    Journal: Bioorg Med Chem Lett; 2007 Feb 15; 17(4):869-73. PubMed ID: 17174089.
    Abstract:
    A series of 4,5-disubstitute-1,2,3-thiadiazole compounds were designed and synthesized as potent anticancer agents, some of them exhibited excellent in vitro and in vivo inhibitory activity.
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