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  • Title: Primary amyloidosis presenting as intrahepatic cholestasis.
    Author: Bandyopadhyay SK, Bandyopadhyay R, Dutta A.
    Journal: Indian J Pathol Microbiol; 2006 Oct; 49(4):557-9. PubMed ID: 17183853.
    Abstract:
    Hepatic involvement in primary amyloidosis is not rare but is often clinically silent. A mild elevation of the serum alkaline phosphatase level and hepatomegaly are the most common findings. We report a case of primary amyloidosis in an adult male presenting with intrahepatic cholestasis where viral, drug, alcohol, and autoimmune etiologies were all excluded and the definite diagnosis was established by liver biopsy with Congo red staining. Subsequently the patient was found to have monoclonal light chain disorder.
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