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  • Title: Regulation of calcitonin release from the 6.23 rat C-cell line by cyclic nucleotide analogues and pharmacological mediators.
    Author: Gilgenkrantz JL, Hall TJ, Chambers TJ.
    Journal: Experientia; 1991 Oct 15; 47(10):1067-9. PubMed ID: 1718775.
    Abstract:
    Calcitonin release from 6.23 rat medullary thyroid carcinoma C-cells was stimulated by dibutyryl cyclic AMP and inhibited by dibutyryl cyclic GMP in concentration dependent fashion. Histamine, isoproterenol, prostaglandin E2 and Bay K 8644 stimulated calcitonin release, while acetylcholine and serotonin had no significant effect on CT release.
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