These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Vitreous levels of interleukin-8 in patients with proliferative diabetic retinopathy.
    Author: Petrovic MG, Korosec P, Kosnik M, Hawlina M.
    Journal: Am J Ophthalmol; 2007 Jan; 143(1):175-6. PubMed ID: 17188064.
    Abstract:
    PURPOSE: To determine the levels of interleukin 8 (IL-8) in the vitreous of patients with proliferative diabetic retinopathy (PDR). DESIGN: Observational case-control study. METHODS: Vitreous fluid samples were obtained by vitreoretinal surgery from 71 eyes of patients with diabetes mellitus type 2 with PDR and from 17 eyes of nondiabetic patients with a macular hole. PDR was classified as active and inactive and subdivided according to the extent of large-vessel gliotic obliteration. The cytokine levels were measured by cytometric bead array method. RESULTS: The vitreous levels of IL-8 were significantly higher in patients with PDR in comparison with the control subjects (P < .001) and in patients with higher extent of large vessel gliotic obliteration (P < .001). A vitreous level of IL-8 was not associated with the presence of active PDR. CONCLUSION: Increased levels of IL-8 in PDR were associated with a higher extent of large-vessel gliotic obliteration.
    [Abstract] [Full Text] [Related] [New Search]