These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Quantitative sensory testing of cold and vibration perception during compression of median nerve at the wrist.
    Author: Tsuboya H, Tani T, Ishida K, Ushida T, Taniguchi S, Kimura J.
    Journal: Muscle Nerve; 2007 Apr; 35(4):458-64. PubMed ID: 17195168.
    Abstract:
    We conducted a sequential study of quantitative sensory testing (QST) during compression-induced conduction block of the median nerve to determine relative vulnerability of the small and large myelinated nerve fibers. We tested cold (CPT) and vibratory perception thresholds (VPT) of the third digit in 15 healthy subjects during constant, localized compression for 30 min of the median nerve at the wrist. The orthodromic sensory nerve action potentials (SNAPs) recorded at wrist and elbow served to monitor the degree of associated conduction block. After the onset of nerve compression, it took 16 min for CPT to show the first change; VPT remained normal for 26 min. CPT recovered 2 min later than VPT after release of compression. The SNAP amplitude at the wrist diminished immediately at the start of compression and declined progressively, whereas the response at the elbow remained the same initially, showing no latency change for 20 min. A nearly identical time course of SNAP changes in the two experiments justified the comparison of separately tested CPT and VPT as a measure of modality-specific vulnerability. Contrary to the common belief, a focal compression sufficient to produce rapidly reversible conduction abnormalities affects the slow-conducting small myelinated fibers mediating cold perception before the fast-conducting large myelinated fibers transmitting vibration perception. The data document the order of modality-specific vulnerability of sensory nerve fibers to mild compression. The finding suggests that testing CPT, rather than VPT, provides a better QST to delineate rapidly reversible symptoms induced by compression.
    [Abstract] [Full Text] [Related] [New Search]