These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Room-temperature, phosphorimetric determination of the beta-blocking agent pindolol in pharmaceutical tablets, urine and blood serum.
    Author: Salinas-Castillo A, Cañabate-Díaz B, Segura-Carretero A, Fernández-Gutiérrez A.
    Journal: Anal Bioanal Chem; 2007 Mar; 387(5):1945-8. PubMed ID: 17203265.
    Abstract:
    It is already recognised that heavy-atom-induced, room-temperature phosphorescence can be used to determine pindolol in pharmaceutical samples and biological fluids. We describe here a new, simple, rapid and selective development of this technique. The phosphorescence signals derive from the interaction of pindolol with a relatively high concentration of heavy-atom salts in the presence of sodium sulphite as oxygen scavenger. Phosphorescence was registered in the presence of 1.2 M potassium iodide, 15 mM sodium sulphite and 30% v/v methanol at 450 nm, exciting at 285 nm. The detection limit was 21.1 ng mL(-1). The method has been successfully applied to the determination of pindolol in commercial pharmaceutical tablets, urine and blood serum.
    [Abstract] [Full Text] [Related] [New Search]