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  • Title: [Fourier transform infrared spectroscopy study on normal and malignant tissues of cervix].
    Author: Li WX, Zheng QQ, Wang P, Li YQ, Chen GH.
    Journal: Guang Pu Xue Yu Guang Pu Fen Xi; 2006 Oct; 26(10):1833-7. PubMed ID: 17205732.
    Abstract:
    Fourier transform infrared spectroscopy (FTIR) was used to investigate 35 cervical tissues , including 17 squamous cell carcinoma of cervical samples, and 5 adenocarcinoma of cervical samples, 13 normal cervical samples. The results show that there are 18 spectral bands with highly appearance percentage(>80%) in these three types of tissues, and these spectral bands may be the characteristic infrared spectra bands for cervical tissues; Some of relative absorbance ratios are statistically significant (p < 0.05) among these three types of tissues. These differences of relative absorbance ratios are mainly centered at 1080, 1238, 1314, 1339, 1397, 1454, 1541, 1647, 2854, 2873, 2926, and 2958 cm(-1). The present results indicate that FTIR can be used to distinguish these three types of tissues. The utilization of FTIR spectra in cervical tissues is expected to be a hopeful method in cervical cancer screening and clinical diagnosis in the future.
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