These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Magnetic brain stimulation: a tool to explore the action of the motor cortex on single human spinal motoneurones.
    Author: Mills KR.
    Journal: Trends Neurosci; 1991 Sep; 14(9):401-5. PubMed ID: 1720580.
    Abstract:
    The human brain can be stimulated by a single intense magnetic pulse over the scalp. Currents induced within the cranium excite the motor cortex and cause limb muscles to contract. The discharge of single motor units, the firing of which is maintained by voluntary effort, can be modulated by magnetic stimuli. Peri-stimulus time histograms suggest that after a cortical stimulus spinal motoneurones are induced to fire by a sequence of EPSPs arising from a train of impulses transmitted monosynaptically over fast-conducting corticospinal fibres. In multiple sclerosis both dispersion of this descending volley and partial transmission failure can impair motoneurone excitation and may explain motor symptoms in these patients.
    [Abstract] [Full Text] [Related] [New Search]