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  • Title: Evaluation of exposure with response-prevention for obsessive compulsive disorder in childhood and adolescence.
    Author: Bolton D, Perrin S.
    Journal: J Behav Ther Exp Psychiatry; 2008 Mar; 39(1):11-22. PubMed ID: 17207457.
    Abstract:
    The present study was undertaken to estimate the effect of exposure plus response-prevention (E/RP), delivered alone intensively over 5-weeks and without concomitant pharmacotherapy, for children and adolescents with OCD. Twenty children and adolescents with OCD, not receiving medication for this condition, were randomized to E/RP or a wait-list condition. Statistically and clinically significant symptomatic improvement was found in the E/RP group compared with controls, with improvement maintained at follow-up an average of 14 weeks later. Effect size in the main intention-to-treat analysis was 1.23 and in the secondary per protocol analysis was 1.64. This study lends further support to the view that E/RP is an effective treatment for childhood OCD.
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