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  • Title: Post-eclosion decline in 'knock-down' thermal resistance and reduced effect of heat hardening in Drosophila melanogaster.
    Author: Pappas C, Hyde D, Bowler K, Loeschcke V, Sørensen JG.
    Journal: Comp Biochem Physiol A Mol Integr Physiol; 2007 Mar; 146(3):355-9. PubMed ID: 17208027.
    Abstract:
    The dependency of knock-down resistance on age, from 0 to 12 days post eclosion, was studied in two lines of Drosophila melanogaster, one selected for knock-down resistance and one unselected control. Additionally, the inducible Hsp70 expression level was assessed at maintenance temperature and after a heat hardening treatment (1 h at 35 degrees C) at the same ages. Knock-down resistance decreased roughly linearly with age in both control and knock-down selected lines and in both sexes regardless of maintenance temperature. Hsp70 expression, however, fell only from day 0 to day 3 and was thereafter changed little. Acclimation did not result in detectable difference between lines. The effect of hardening was only significant for control flies. This suggests that the increased knock-down resistance of the selected line was reached at the expense of hardening ability.
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