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  • Title: Identification of myenteric neurons which project to the mucosa of the guinea-pig small intestine.
    Author: Song ZM, Brookes SJ, Costa M.
    Journal: Neurosci Lett; 1991 Aug 19; 129(2):294-8. PubMed ID: 1720880.
    Abstract:
    Myenteric neurons which innervate the mucosa of the guinea-pig ileum were characterized by combining retrograde transport of DiI in vitro with immunohistochemistry. Of DiI-labelled myenteric neurons, 43% were immunoreactive for calbindin and substance P, 25% were immunoreactive for calbindin alone, and 18% were immunoreactive for substance P alone. These 3 classes of neurons had Dogiel Type II morphology and are probably sensory neurons. Two classes of probable secretomotor neurons were characterized by immunoreactivity for neuropeptide Y (4%) and vasoactive intestinal peptide (2%). These 5 classes of myenteric neurons represent over 90% of the retrogradely labelled myenteric neurons that project to the mucosa.
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