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  • Title: Clinical usefulness of antibodies against Babesia gibsoni detected by ELISA with recombinant P50.
    Author: Miyama T, Inokuma H, Itamoto K, Okuda M, Verdida RA, Xuan X.
    Journal: J Vet Med Sci; 2006 Dec; 68(12):1371-3. PubMed ID: 17213713.
    Abstract:
    The clinical usefulness of antibodies against Babesia gibsoni detected by ELISA with recombinant P50 was examined in dogs in an area where B. gibsoni infection was endemic. Only 8 among 14 dogs with acute type B. gibsoni infection without a previous history of infection were positive. This high percentage of false-negative results is thought to be a weak point of ELISA as a diagnostic tool. However, 14 other anemic dogs with a confirmed history of B. gibsoni infection were all positive, thus confirming the higher sensitivity of ELISA in detecting a history of infection.
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