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  • Title: Intravascular lymphomatosis mimicks a cerebral demyelinating disorder.
    Author: Liew CL, Shyu WC, Tsao WL, Li H.
    Journal: Acta Neurol Taiwan; 2006 Dec; 15(4):264-8. PubMed ID: 17214091.
    Abstract:
    Intravascular lymphomatosis is a rare extra-nodal form of diffuse, large B-cell non-Hodgkin's lymphoma that causes a myriad of neurological symptoms, including focal neurological deficits, cognitive decline, and seizure. Intravascular lymphomatosis is difficult to make ante-mortem diagnosis because of its variable clinical presentation and non-specific laboratory findings. Neuroimaging findings also vary widely in patients of intravascular lymphomatosis. We present, herein, a patient with rapidly deteriorating neurological deficit whose brain MRI revealed rapidly progressing white matter diseases. This patient was diagnosed and treated as having a cerebral demyelinating disorder. Intravascular lymphomatosis involving multiple organs was finally diagnosed after autopsy.
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