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  • Title: Colonic squamous cell carcinoma in ulcerative colitis: Report of a case and review of the literature.
    Author: Cheng H, Sitrin MD, Satchidanand SK, Novak JM.
    Journal: Can J Gastroenterol; 2007 Jan; 21(1):47-50. PubMed ID: 17225882.
    Abstract:
    Squamous cell carcinoma (SCC) is a rare neoplasm in the colorectum. A case of SCC rising from an area of squamous metaplasia in the rectum is presented in a patient with long-standing ulcerative colitis and perianal warts. This is the first report in the literature describing the evolution of squamous metaplasia in the colonic mucosa into invasive carcinoma over time. Related literature on colorectal SCC and squamous metaplasia, and their relationships with inflammatory bowel disease and human papilloma virus, is reviewed. Un carcinome squameux colique (CSC) est un néoplasme rare du colorectum. Un cas de CSC trouvant son origine dans un foyer de métaplasie squameuse du rectum s’est manifesté chez un patient atteint d’une colite ulcéreuse de longue date et de condylomes périanaux. C’est le premier rapport publié décrivant l’évolution d’une métaplasie squameuse de la muqueuse colique en carcinome envahissant. Sont également analysées les publications connexes sur le CSC colorectal et la métaplasie squameuse, de même que sur leur relation avec les maladies inflammatoires de l’intestin et le papillomavirus.
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