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  • Title: Characterization of Plasmodium vivax heat shock protein 70 and evaluation of its value for serodiagnosis of tertian malaria.
    Author: Na BK, Park JW, Lee HW, Lin K, Kim SH, Bae YA, Sohn WM, Kim TS, Kong Y.
    Journal: Clin Vaccine Immunol; 2007 Mar; 14(3):320-2. PubMed ID: 17229883.
    Abstract:
    We have characterized Plasmodium vivax heat shock protein 70 (PvHSP70) and evaluated serodiagnostic applicability of recombinant PvHSP70 (rPvHSP70). In enzyme-linked immunosorbent assays and immunoblot analyses, rPvHSP70 showed high sensitivity (88.8%; 203/228 cases). P. falciparum-infected sera revealed positive reactions (78.8%). The predominant immunoglobulin G (IgG) subclasses were segregated with IgG1 and IgG3.
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