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  • Title: Supranuclear vertical gaze abnormalities in sporadic Creutzfeldt-Jakob disease.
    Author: Prasad S, Ko MW, Lee EB, Gonatas NK, Stern MB, Galetta S.
    Journal: J Neurol Sci; 2007 Feb 15; 253(1-2):69-72. PubMed ID: 17234215.
    Abstract:
    Supranuclear gaze palsies are an uncommon feature of Creutzfeldt-Jakob disease (CJD). Most reported cases of CJD with features of supranuclear gaze palsy are familial. We report 2 patients with supranuclear vertical gaze abnormalities associated with spongiform changes in the midbrain. Both patients were found to have sporadic CJD after genetic testing. Distinguishing familial from sporadic CJD in this setting has important genetic and epidemiological implications.
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