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  • Title: Hepcidin the link between inflammation and anemia in chronic renal failure.
    Author: Atanasiu V, Manolescu B, Stoian I.
    Journal: Rom J Intern Med; 2006; 44(1):25-33. PubMed ID: 17236285.
    Abstract:
    A chronic inflammatory state characterized the patients with chronic renal failure. The causes of this situation are multiple and inter-connected. The break of the equilibrium between pro-inflammatory agents and anti-inflammatory ones in haemodialysis patients leads to anemia of chronic inflammation, characterized by a functional iron deficiency. Very recently it was discovered a peptide produced by the liver, named hepcidin, that provides a good link between inflammation and metabolism of iron, rendering more understandable the interdependence of inflammation and anemia.
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