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  • Title: Human leucocyte antigen and insulin dependent diabetes mellitus.
    Author: Gupta MM, Raghunath D, Kher SK, Radhakrishnan AP.
    Journal: J Assoc Physicians India; 1991 Jul; 39(7):540-3. PubMed ID: 1724775.
    Abstract:
    HLA typing was done in 25 cases of insulin dependent diabetes mellitus (IDDM) and compared with 60 healthy controls. There was a significantly increased frequency of HLA B-8, HLA B-12 and HLA DR-3 in IDDMO. The odds ratio (relative risk) of developing IDDM for HLA B-8 was 4.42 (p less than 0.10), for HLA B-12 was 3.56 (p less than 0.10) and for HLA DR3 9.75 (p less than 0.001). There was no correlation of HLA specificity with complications of diabetes.
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