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  • Title: One-pot approach to chiral chromenes via enantioselective organocatalytic domino oxa-Michael-aldol reaction.
    Author: Li H, Wang J, E-Nunu T, Zu L, Jiang W, Wei S, Wang W.
    Journal: Chem Commun (Camb); 2007 Feb 07; (5):507-9. PubMed ID: 17252110.
    Abstract:
    A highly enantioselective (S)-diphenylpyrrolinol triethylsilyl ether promoted tandem oxa-Michael-aldol reaction of alpha,beta-unsaturated aldehydes with salicylaldehydes has been developed; the method affords one-pot access to chiral and synthetically useful chromenes in high yields and high enantioselectivities from readily available compounds.
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