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  • Title: Efficient ruthenium and copper cocatalzyed five-component coupling to form dipropargyl amines under mild conditions in water.
    Author: Bonfield ER, Li CJ.
    Journal: Org Biomol Chem; 2007 Feb 07; 5(3):435-7. PubMed ID: 17252122.
    Abstract:
    Dipropargyl amines are synthesized by a double direct alkynylation of primary followed by secondary imines formed in situ during an efficient, five-component, one-pot coupling reaction cocatalyzed by ruthenium and copper in water.
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