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  • Title: Bronchioloalveolar carcinoma in congenital cystic adenomatoid malformation of lung.
    Author: West D, Nicholson AG, Colquhoun I, Pollock J.
    Journal: Ann Thorac Surg; 2007 Feb; 83(2):687-9. PubMed ID: 17258019.
    Abstract:
    Congenital cystic adenomatoid malformation (CCAM) of lung is a rare condition with the potential for malignant transformation. We report a patient who underwent lobectomy for a cystic lung lesion, which was found to be a type 1 CCAM associated with a mucinous bronchioloalveolar carcinoma. Retrospective review of a biopsy specimen from the same lobe excised during an ipsilateral empyema drainage 11 years previously showed similar foci of bronchioloalveolar carcinoma. The patient remains well 3 years after surgery. This case demonstrates the indolent nature of malignancies seen in association with type 1 CCAMs and also that complete excision, probably by lobectomy, is the treatment of choice to avoid recurrence.
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