These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Efficacy and tolerability of high dose sublingual immunotherapy in patients with rhinoconjunctivitis.
    Author: Worm M.
    Journal: Eur Ann Allergy Clin Immunol; 2006 Dec; 38(10):355-60. PubMed ID: 17274520.
    Abstract:
    In a multi-centre, randomized, double-blind, placebo-controlled clinical trial over 3 years high dose sublingual specific immunotherapy with an extract of a 6-grass-pollen mixture showed a highly significant and clinically relevant improvement in patients with grass pollen rhinitis/-conjunctivitis with or without asthma and an increase in allergen specific antibodies (IgG1, IgG4) indicating immunological efficacy. A difference of 46% in mean symptom medication score between active and placebo group was seen. The treatment with the sublingual solution was well tolerated. High dose sublingual immunotherapy can therefore be considered as an efficient therapeutic option in the management of IgE-mediated allergic airway diseases.
    [Abstract] [Full Text] [Related] [New Search]