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  • Title: [Auto-antibodies against glutamic acid decarboxylase and diabetes].
    Author: Mandrup-Poulsen TR.
    Journal: Ugeskr Laeger; 2007 Jan 22; 169(4):300-4. PubMed ID: 17274923.
    Abstract:
    The 1999 WHO classification delineates immune mediated type 1 diabetes from other types of diabetes by the presence of auto-antibodies against beta-cell constituents. The GAD65 auto-antibody test is the method of first choice because it has the highest sensitivity, specificity and positive predictive value and is the most standardized and well-characterized type 1 diabetes related auto-antibody analysis. It is recommended that demonstration of GAD auto-antibodies leads to diagnosis, classification or re-classification of diabetes patients as immune mediated type 1 diabetes.
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