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Title: Synthesis and antibacterial activity of 4,5,6,7-tetrahydro-thieno[3,2-c]pyridine quinolones. Author: Srivastava BK, Solanki M, Mishra B, Soni R, Jayadev S, Valani D, Jain M, Patel PR. Journal: Bioorg Med Chem Lett; 2007 Apr 01; 17(7):1924-9. PubMed ID: 17276057. Abstract: Synthesis and antibacterial activity of a number of substituted 4,5,6,7-tetrahydro-thieno[3,2-c]pyridine quinolones is reported. The antibacterial activities were evaluated in standard in vitro MIC assay method. Some of the compounds showed in vitro (MIC) antibacterial activity comparable to those of Gatifloxacin, Ciprofloxacin, and Sparfloxacin.[Abstract] [Full Text] [Related] [New Search]