These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The pathogenetic role of HLA-B27 and its subtypes.
    Author: Khan MA, Mathieu A, Sorrentino R, Akkoc N.
    Journal: Autoimmun Rev; 2007 Jan; 6(3):183-9. PubMed ID: 17289555.
    Abstract:
    The strong association between HLA-B27 and ankylosing spondylitis has been known for more than 33 years, but the enigma of the pathogenetic role of the gene and its product has not yet been solved. Ongoing studies have produced evidence supporting different theories to explain this association, and structural and functional studies of HLA-B27 allele products at molecular level have provided information of broad and multidisciplinary value and disclosed new avenues leading to autoimmunity and immune disregulation.
    [Abstract] [Full Text] [Related] [New Search]