These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Formation of high-resistance supported lipid bilayer on the surface of a silicon substrate with microelectrodes.
    Author: Urisu T, Rahman MM, Uno H, Tero R, Nonogaki Y.
    Journal: Nanomedicine; 2005 Dec; 1(4):317-22. PubMed ID: 17292105.
    Abstract:
    We have developed two basic technologies for fabrication of supported planar lipid bilayer membrane ion channel biosensors: a defect-free lipid bilayer formation on the substrate surface with electrode pores and a patterning technique for the hydrophobic self-assembled-monolayer to form the guard ring that reduces the lipid bilayer edge-leak current. The importance of the supported-membrane structure to achieve low noise and high-speed performance is suggested on the basis of the observed relation between the single-ion-channel current noise and the pore size.
    [Abstract] [Full Text] [Related] [New Search]