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  • Title: [A rare case of large-cell gastric lymphoma in a patient with chronic lympholeucosis].
    Author: Simonenko VB, Frank GA, Zavalishina LE, Makanin MA, Ostrovskaia EIu, Beliaev LB, Dulin PA.
    Journal: Klin Med (Mosk); 2006; 84(12):62-4. PubMed ID: 17294889.
    Abstract:
    Chronic lympholeucosis (CLL) is a B-cell lymphoproliferative disease, the morphological substrate of which is a clone of lymphocytes similar in size and morphology to normal mature lymphocyte and similar in immunophenotype to B lymphocytes at late stages of differentiation. The occurrence of large-cell lymphoma against the background of B-CLL is called Richter syndrome. A new tumor may occur in lymph nodes, the spleen, the liver, and the gastrointestinal tract (GIT). GIT involvement in Richter syndrome is a very rare case; the authors found only six descriptions of such cases in available literature, and no such description in Russian literature. The authors adduce their own observation.
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