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  • Title: [Predictive factors of intestinal stenosis in Crohn's disease].
    Author: Elloumi H, Ben Abdelaziz A, Sfar S, Arfaoui D, Ben Slama A, Ghouma M, Ajmi S.
    Journal: Tunis Med; 2006 Nov; 84(11):711-3. PubMed ID: 17294896.
    Abstract:
    UNLABELLED: The aim of our study was to determine demographic, clinical, biological or endoscopic factors that predict intestinal stenosis in Crohn's disease. PATIENTS AND METHODS: One hundred and twenty one patients were retrospectively analyzed during 10 years. The diagnosis of stenosis were determined by morphologic and endoscopic exams independently of appearance of symptoms. The studied characteristics were age at appearance of symptoms, sex, geographical origin, tobacco addiction, symptoms revealing Crohn's disease, extra-digest and auto-immune signs associate and seat of disease. Biological values studied were: haemoglobin, white cells, platelet, erythrocyte sedimentation rate, C- reactive protein and albumin. Predictive factors were assessed using univariate and multivariate analysis. RESULTS: Forty-seven patients (38,8%) had a stenosis. In univariate analysis, predictive factors of stenosis were a young age and ileum site of Crohn's disease. In multivariate analysis, none of these variables was independently associated of appearance of stenosis in Crohn's disease. CONCLUSION: This study didn't identify the presence of predictive factors of intestinal stenosis in Crohn's disease that could allow an early specific therapy.
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