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  • Title: [Evaluation on effects of disassembled formulas of Xuefu Zhuyu Decoction for treatment of angina pectoris using Seattle Angina Questionnaire].
    Author: Jing L, Wang J, Wang T.
    Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi; 2007 Jan; 27(1):18-20. PubMed ID: 17302057.
    Abstract:
    OBJECTIVE: To evaluate the therapeutic effect of disassembled formulas of Xuefu Zhuyu Decoction (XZD) for treatment of angina pectoris (AP) of coronary heart disease (CHD) using Seattle Angina Questionnaire (SAQ). METHODS: One hundred and twenty-three AP patients were randomly assigned to the XZD group, the refined XZD group, the drug-pair group and the placebo group. The therapeutic effect on scores in various aspects, including anginal stability ( I ), anginal attack frequency (II), satisfaction on treatment (II) and cognitive level on disease (IV) of patients was evaluated using SAQ before and after treatment. RESULTS: After treatment, improvement was shown on scores of I , II and III in the XZD group, on those of all the four scores in the refined XZD group, on those of scores I and II in the drug-pair group and in the placebo group only on scores of I was improved significantly (P < 0.05 or P < 0.01). The improvement on scores of I in the 3 treated groups was better significantly than that in the placebo group (P < 0.05). CONCLUSION: It is feasible to evaluate the therapeutic effect of disassembled formulas of XZD on AP of CHD with SAQ; XZD and its disassembled formulas shows better effects than that of placebo in improving the condition of angina attack.
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