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  • Title: Wavelet-based analysis of MMN responses in children.
    Author: Burger M, Hoppe U, Kummer P, Lohscheller J, Eysholdt U, Döllinger M.
    Journal: Biomed Tech (Berl); 2007 Feb; 52(1):111-6. PubMed ID: 17313345.
    Abstract:
    Event-related potentials (ERPs) as part of the EEG are applied to assess auditory processing in children. Mismatch negativity (MMN) is a change-specific component of ERPs that indicates a pre-cognitive discrimination process. MMN responses were recorded in 10 healthy preschool children to four different types of signal changes. The signals investigated were processed using a discrete wavelet transform (DWT) to analyze the characteristics of the ERP components. All children showed distinct MMN that was significant in all tasks. The MMN amplitudes varied between subjects and depended on the different tasks. The wavelet transform allowed simplified analysis and quantification of the MMN component, as well as the double-peak structure of the P1 component. The variation in MMN amplitudes suggests the possibility of determining individual auditory profiles. Owing to the shorter time required, the MMN paradigm suggested combined with the DWT proposed offers a new objective investigation method for children.
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