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  • Title: Encephalopathy after furosemide use in nephrotic syndrome.
    Author: Sharma AP, Grimmer J.
    Journal: J Paediatr Child Health; 2007 Mar; 43(3):188-90. PubMed ID: 17316196.
    Abstract:
    An 18-year-old girl with nephrotic syndrome presented with a life-threatening respiratory failure and a severe encephalopathy, shortly after being started on furosemide. The evaluation confirmed furosemide as the sole culprit for the clinical manifestations. This case highlights an unpredictable dose-response relationship of furosemide. The pathophysiological basis, differential diagnosis and clinical implications of the observed findings are discussed.
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