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  • Title: Antiproliferative xanthones of Terminalia calcicola from the Madagascar rain forest.
    Author: Cao S, Brodie PJ, Miller JS, Randrianaivo R, Ratovoson F, Birkinshaw C, Andriantsiferana R, Rasamison VE, Kingston DG.
    Journal: J Nat Prod; 2007 Apr; 70(4):679-81. PubMed ID: 17323994.
    Abstract:
    A bioassay-guided fractionation of the EtOH extract of the Madagascan plant Terminalia calcicola led to the isolation of two new cytotoxic xanthones, termicalcicolanone A (1) and termicalcicolanone B (2). The structures of the new compounds were established on the basis of one- and two-dimensional NMR spectroscopic data. Both compounds showed modest antiproliferative activity toward the A2780 human ovarian cancer cell line.
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