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  • Title: [Study on supercritical carbon dioxide fluid extraction process of lignans from Kadsura heteroclita (Roxb.) Craib].
    Author: Li XG, Gao Q, Weng W, Luo HM.
    Journal: Zhong Yao Cai; 2006 Oct; 29(10):1096-8. PubMed ID: 17326414.
    Abstract:
    OBJECTIVE: To optimize supercritical carbon dioxide fluid extraction process parameters of lignans from Kadsura heteroclita (Roxb.) Craib. METHODS: The supercritical carbon dioxide fluid extraction was adopted to extract lignans. The contents of total lignans and gamma-schisandrin were determined to test the influence of pressure, temperature, grinding particle size and flow rate of CO2. RESULTS: The extraction pressure and grinding particle size had significant effects on the content of total lignans and gamma-schisandrin. However, The extraction temperature and flow rate of CO2 had no significant effect on them. CONCLUSION: The optimum process parameters are as fouons: pressure is 10 MPa, temperature is 45 degrees C, flow rate of CO2 is 30 L/h and herbs are granulated.
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