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  • Title: [A possibility of using increased oxygen consumption as a criterion for mechanical respiration weaning in pediatric practice].
    Author: Grigoliia GN, Chokhonelidze IK, Gvelesiani LG, Sulakvelidze KR, Tutberidze KN.
    Journal: Georgian Med News; 2007 Jan; (142):7-10. PubMed ID: 17327624.
    Abstract:
    The body oxygen consumption and the oxygen cost of breathing (which is the difference in oxygen consumption measured during controlled ventilation and again during spontaneous ventilation) were measured in 46 children with congenital heart diseases after open-heart surgery. There was a significant exponential correlation between the body oxygen consumption (ml/m(2)/min) and the oxygen cost of breathing as a percentage of total oxygen consumption during spontaneous ventilation and the duration of weaning in minutes (r=+0,882, p<0,02). Therefore, as the oxygen cost of breathing was correlated with the total weaning time, this may be a useful index on the weaning process (sensitivity 92%, specificity 85%).
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