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  • Title: Relationship between elongation factor I- and elongation factor II- dependent guanosine triphosphatase activities of ribosomes. Inhibition of both activities by ricin.
    Author: Sperti S, Montanaro L, Mattioli A, Testoni G.
    Journal: Biochem J; 1975 Jun; 148(3):447-51. PubMed ID: 173282.
    Abstract:
    The elongation factor 1- and elongation factor 2-dependent GTPase (guanosine triphosphatase) activities of ribosomes are inhibited by ricin, a toxic protein known to inactivate the 60S ribosomal subunit. It is suggested that also in eukaryotic ribosomes a "GTPase site', located on the larger subunit, is common to the two elongation factors.
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