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Title: The effects of adenine nucleotides and guanine nucleotides on urate synthesis de novo by isolated chick liver and kidney cells. Author: Badenoch-Jones P, Buttery PJ. Journal: Biochem J; 1975 Jun; 148(3):599-601. PubMed ID: 173289. Abstract: Isolated chick liver and kidney cells produce urate de novo from glycine, and this is partially inhibited by 1 mm-AMP and by 1 mm-GMP in liver cells but not in kidney cells. Azaserine fully inhibits this synthesis de novo, but attempts to isolate formylglycine amide ribonucleotide from azaserine-blocked cells were unsuccessful.[Abstract] [Full Text] [Related] [New Search]