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  • Title: Auditory event-related potentials in Parkinson's disease: prominent correlation with attention.
    Author: Matsui H, Nishinaka K, Oda M, Kubori T, Udaka F.
    Journal: Parkinsonism Relat Disord; 2007 Oct; 13(7):394-8. PubMed ID: 17329143.
    Abstract:
    OBJECTIVE: Auditory P300 has been reported to be abnormal in demented patients with Parkinson's disease. However, it is still controversial which factors in Parkinson's disease influence P300 parameters. METHODS: Forty patients with Parkinson's disease were included. Patients were divided into two groups: patients with dementia (PDD) and without dementia (PDND). An 'odd-ball' paradigm was used for auditory event-related potentials. RESULTS: P300 latency was markedly delayed in PDD patients. Age and DRS1 (attention) were the most important factors influencing P300 latency. CONCLUSIONS: Although there have been reports of P300 in the past, its abnormalities reflect the deficit of attention in Parkinson's disease.
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